There are at present two types of the commercially available SI analyzers on the market:
- conventional SIA system (A)
- microSIA–LOV instrument (B, C)
The conventional instrument is configured by connecting the individual components (pump, valve, coils and detector) by tubing. Marketed by Global FIA as Flo Pro system the instrument is available several configurations, and detector options including spectrophotometry, fluorescence and chemiluminescence. The unique feature of the system is the Miligat pump, since it is continuously refilling and provides wider range of flow rates than a conventional syringe pump.
The microSI-LOV instruments are smallest automated analyzers available on the market. Their unique feature is the lab-on-valve (LOV) configuration that integrates valve functions, flow channels and detector, within a single monolithic unit mounted atop a multiposition valve. As a result these instrument use microliter volumes of samples and reagents.
When configured with synchronously refilling pump (B) , the microSI-LOV system is sutable for both fast and high sensitivity assays. MicroSI-LOV instruments are compatible with UV-VIS, fluorescence, chemiluminiscence and voltammetry and their combinations. These modes of detection, are all carried out in a flow cell integrated within the LOV module. For spectrophotometry, the long light path flow cell with up to 50cm long light path can be directly mounted onto the LOV module. The microSI-LOV instrument is the only commercial instrument suitable for automation of the Bead Injection Technique (Chapter 3)